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RORA rabbit monoclonal antibody

  • Catalog # : H00006095-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RORA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RORA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RORA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 6095
  • GeneBank Accession#:
  • RORA
  • Gene Name:
  • RORA
  • Gene Alias:
  • DKFZp686M2414,MGC119326,MGC119329,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA
  • Gene Description:
  • RAR-related orphan receptor A
  • Gene Summary:
  • The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • RAR-related orphan receptor alpha,ROR-alpha,retinoic acid receptor-related orphan receptor alpha,retinoid-related orphan receptor alpha,transcription factor RZR-alpha
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