RORA rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RORA peptide using ARM Technology.
Immunogen
A synthetic peptide of human RORA is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RORA peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RORA
Entrez GeneID
6095GeneBank Accession#
RORAGene Name
RORA
Gene Alias
DKFZp686M2414, MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA
Gene Description
RAR-related orphan receptor A
Omim ID
600825Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
RAR-related orphan receptor alpha|ROR-alpha|retinoic acid receptor-related orphan receptor alpha|retinoid-related orphan receptor alpha|transcription factor RZR-alpha
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Interactome
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Disease
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