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ROBO1 Pre-design Chimera RNAi

  • Catalog # : H00006091-R03
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  • Specification
  • Product Description:
  • Homo sapiens roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1), transcript variants, mRNA. This product targets for all of 3 transcript variants.
    (NM_001145845.1,NM_002941.3,NM_133631.3)
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001145845.1,NM_002941.3,NM_133631.3
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6091
  • Gene Name:
  • ROBO1
  • Gene Alias:
  • DUTT1,FLJ21882,MGC131599,MGC133277,SAX3
  • Gene Description:
  • roundabout, axon guidance receptor, homolog 1 (Drosophila)
  • Gene Summary:
  • Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • axon guidance receptor,roundabout 1
  • Gene Pathway
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