RNF6 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RNF6 partial ORF ( NP_005968, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNLLGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RNF6
Entrez GeneID
6049GeneBank Accession#
NM_005977Protein Accession#
NP_005968Gene Name
RNF6
Gene Alias
DKFZp686P0776
Gene Description
ring finger protein (C3H2C3 type) 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq
Other Designations
OTTHUMP00000018154|OTTHUMP00000018155|OTTHUMP00000018156|RING-H2 protein RNF-6|ring finger protein 6
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