RNF6 monoclonal antibody (M01), clone 3B1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RNF6.
Immunogen
RNF6 (NP_005968, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNLLGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RNF6 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — RNF6
Entrez GeneID
6049GeneBank Accession#
NM_005977Protein Accession#
NP_005968Gene Name
RNF6
Gene Alias
DKFZp686P0776
Gene Description
ring finger protein (C3H2C3 type) 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq
Other Designations
OTTHUMP00000018154|OTTHUMP00000018155|OTTHUMP00000018156|RING-H2 protein RNF-6|ring finger protein 6
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