RNASE1 monoclonal antibody (M01), clone 1E5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RNASE1.
Immunogen
RNASE1 (NP_002924.1, 29 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — RNASE1
Entrez GeneID
6035GeneBank Accession#
NM_002933Protein Accession#
NP_002924.1Gene Name
RNASE1
Gene Alias
MGC12408, RIB1, RNS1
Gene Description
ribonuclease, RNase A family, 1 (pancreatic)
Omim ID
180440Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
RNase upI-1|pancreatic ribonuclease
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Interactome
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Disease
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