RLN1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RLN1 protein.
Immunogen
RLN1 (NP_008842.1, 1 a.a. ~ 185 a.a) full-length human protein.
Sequence
MPRLFLFHLLEFCLLLNQFSRAVAAKWKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKAALSERQPSLPELQQYVPALKDSNLSFEEFKKLIRNRQSEAADSNPSELKYLGLDTHSQKKRRPYVALFEKCCLIGCTKRSLAKYC
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RLN1 expression in transfected 293T cell line (H00006013-T01) by RLN1 MaxPab polyclonal antibody.
Lane 1: RLN1 transfected lysate(21.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RLN1
Entrez GeneID
6013GeneBank Accession#
NM_006911.2Protein Accession#
NP_008842.1Gene Name
RLN1
Gene Alias
H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Gene Description
relaxin 1
Omim ID
179730Gene Ontology
HyperlinkGene Summary
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet. [provided by RefSeq
Other Designations
OTTHUMP00000021026|preprorelaxin H1|prorelaxin|relaxin H1
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