RHO rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RHO peptide using ARM Technology.
Immunogen
A synthetic peptide of human RHO is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RHO peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RHO
Entrez GeneID
6010GeneBank Accession#
RHOGene Name
RHO
Gene Alias
CSNBAD1, MGC138309, MGC138311, OPN2, RP4
Gene Description
rhodopsin
Omim ID
180380Gene Ontology
HyperlinkGene Summary
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq
Other Designations
opsin 2, rod pigment|retinitis pigmentosa 4, autosomal dominant|rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)
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Interactome
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Disease
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