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Last updated: 2016/12/4

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RHO rabbit monoclonal antibody

  • Catalog # : H00006010-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RHO peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RHO is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RHO peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6010
  • GeneBank Accession#:
  • RHO
  • Gene Name:
  • RHO
  • Gene Alias:
  • CSNBAD1,MGC138309,MGC138311,OPN2,RP4
  • Gene Description:
  • rhodopsin
  • Gene Summary:
  • Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq
  • Other Designations:
  • opsin 2, rod pigment,retinitis pigmentosa 4, autosomal dominant,rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)
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