RHEB MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RHEB protein.
Immunogen
RHEB (NP_005605, 1 a.a. ~ 184 a.a) full-length human protein.
Sequence
MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Cell lysate)
RHEB MaxPab polyclonal antibody. Western Blot analysis of RHEB expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of RHEB expression in transfected 293T cell line (H00006009-T01) by RHEB MaxPab polyclonal antibody.
Lane 1: RHEB transfected lysate(20.24 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RHEB
Entrez GeneID
6009GeneBank Accession#
NM_005614Protein Accession#
NP_005605Gene Name
RHEB
Gene Alias
MGC111559, RHEB2
Gene Description
Ras homolog enriched in brain
Omim ID
601293Gene Ontology
HyperlinkGene Summary
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq
Other Designations
GTP-binding protein Rheb|Ras homolog enriched in brain 2
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Interactome
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Pathway
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Disease
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