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RHD rabbit monoclonal antibody

  • Catalog # : H00006007-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RHD peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RHD is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RHD peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6007
  • GeneBank Accession#:
  • RHD
  • Gene Name:
  • RHD
  • Gene Alias:
  • CD240D,DIIIc,MGC165007,RH,RH30,RHCED,RHDVA(TT),RHDel,RHPII,RHXIII,Rh4,RhDCw,RhII,RhK562-II,RhPI
  • Gene Description:
  • Rh blood group, D antigen
  • Gene Summary:
  • The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • D antigen (DCS),OTTHUMP00000003536,RH polypeptide 2,Rh blood group D antigen,Rh blood group antigen Evans,Rhesus system D polypeptide
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