RGS13 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human RGS13 full-length ORF ( NP_002918.1, 1 a.a. - 159 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
45.5
Interspecies Antigen Sequence
Mouse (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RGS13
Entrez GeneID
6003GeneBank Accession#
NM_002927.3Protein Accession#
NP_002918.1Gene Name
RGS13
Gene Alias
MGC17173
Gene Description
regulator of G-protein signaling 13
Omim ID
607190Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq
Other Designations
OTTHUMP00000033593|regulator of G-protein signalling 13
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Interactome
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Disease
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