RGS2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RGS2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RGS2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RGS2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RGS2
Entrez GeneID
5997GeneBank Accession#
RGS2Gene Name
RGS2
Gene Alias
G0S8
Gene Description
regulator of G-protein signaling 2, 24kDa
Omim ID
600861Gene Ontology
HyperlinkGene Summary
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq
Other Designations
G0 to G1 switch regulatory 8, 24kD|OTTHUMP00000033592|OTTHUMP00000060765|cell growth-inhibiting protein 31|regulator of G-protein signalling 2, 24kD|regulator of G-protein signalling 2, 24kDa
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