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Last updated: 2016/10/16

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RGS1 rabbit monoclonal antibody

  • Catalog # : H00005996-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RGS1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RGS1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RGS1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 5996
  • GeneBank Accession#:
  • RGS1
  • Gene Name:
  • RGS1
  • Gene Alias:
  • 1R20,BL34,IER1,IR20
  • Gene Description:
  • regulator of G-protein signaling 1
  • Gene Summary:
  • This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq
  • Other Designations:
  • B-cell activation protein BL34,OTTHUMP00000033591,early response protein 1R20,immediate-early response 1, B-cell specific,regulator of G-protein signalling 1
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