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Last updated: 2016/12/4
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RGS1 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00005996-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human RGS1 protein.
  • Immunogen:
  • RGS1 (AAH15510, 1 a.a. ~ 196 a.a) full-length human protein.
  • Sequence:
  • MPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPRKAEEIYKAFVHLDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of RGS1 expression in transfected 293T cell line (H00005996-T01) by RGS1 MaxPab polyclonal antibody.

    Lane 1: RGS1 transfected lysate(21.67 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5996
  • Gene Name:
  • RGS1
  • Gene Alias:
  • 1R20,BL34,IER1,IR20
  • Gene Description:
  • regulator of G-protein signaling 1
  • Gene Summary:
  • This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq
  • Other Designations:
  • B-cell activation protein BL34,OTTHUMP00000033591,early response protein 1R20,immediate-early response 1, B-cell specific,regulator of G-protein signalling 1
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