RFX4 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RFX4 protein.
Immunogen
RFX4 (NP_115880.2, 1 a.a. ~ 641 a.a) full-length human protein.
Sequence
MNWAAFGGSEFFIPEGIQIDSRCPLSRNITEWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RFX4 expression in transfected 293T cell line (H00005992-T01) by RFX4 MaxPab polyclonal antibody.
Lane 1: RFX4 transfected lysate(70.51 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RFX4
Entrez GeneID
5992GeneBank Accession#
NM_032491.3Protein Accession#
NP_115880.2Gene Name
RFX4
Gene Alias
NYD-SP10
Gene Description
regulatory factor X, 4 (influences HLA class II expression)
Omim ID
603958Gene Ontology
HyperlinkGene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
regulatory factor X4|regulatory factor X4, isoform c|transcription factor NYD-sp10
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Interactome
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Disease
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Publication Reference
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T cell reactivity to regulatory factor X4 in type 1 narcolepsy.
Guo Luo, Selina Yogeshwar, Ling Lin, Emmanuel Jean-Marie Mignot.
Scientific Reports 2021 Apr; 11(1):7841.
Application:Flow Cyt, WB-Tr, Human, HEK 293T cells.
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T cell reactivity to regulatory factor X4 in type 1 narcolepsy.
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