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Western Blot

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

RFX2

Gene Alias

FLJ14226

Gene Description

regulatory factor X, 2 (influences HLA class II expression)

Omim ID

Gene Ontology

Gene Summary

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq

Other Designations

DNA binding protein RFX2|HLA class II regulatory factor RFX2|regulatory factor X2|trans-acting regulatory factor 2