RFC2 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RFC2 protein.
Immunogen
RFC2 (NP_002905.2, 1 a.a. ~ 320 a.a) full-length human protein.
Sequence
MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RFC2 MaxPab polyclonal antibody. Western Blot analysis of RFC2 expression in HeLa.Western Blot (Cell lysate)
RFC2 MaxPab polyclonal antibody. Western Blot analysis of RFC2 expression in HL-60.Western Blot (Transfected lysate)
Western Blot analysis of RFC2 expression in transfected 293T cell line (H00005982-T02) by RFC2 MaxPab polyclonal antibody.
Lane 1: RFC2 transfected lysate(35.2 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to RFC2 on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RFC2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RFC2
Entrez GeneID
5982GeneBank Accession#
NM_002914Protein Accession#
NP_002905.2Gene Name
RFC2
Gene Alias
A1, MGC3665, RFC40
Gene Description
replication factor C (activator 1) 2, 40kDa
Omim ID
600404Gene Ontology
HyperlinkGene Summary
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
activator 1|replication factor C 2
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Interactome
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Pathway
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Disease
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