RFC1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RFC1 partial ORF ( AAH51786, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISET
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.51
Interspecies Antigen Sequence
Mouse (75); Rat (77)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RFC1
Entrez GeneID
5981GeneBank Accession#
BC051786Protein Accession#
AAH51786Gene Name
RFC1
Gene Alias
A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Gene Description
replication factor C (activator 1) 1, 145kDa
Omim ID
102579Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq
Other Designations
MHC binding factor, beta|replication factor C (activator 1) 1 (145kD)|replication factor C large subunit|replication factor C1
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Interactome
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Pathway
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Disease
- Abnormalities
- Abruptio Placentae
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer disease
- Anemia
- Aneuploidy
- Arthritis
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