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RET 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005979-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-RET full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 119.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-RET antibody (H00005979-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005979-T01
    RET transfected lysate.
    Western Blot
    QC Testing of H00005979-T01
    Lane 1: RET transfected lysate ( 119.8 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5979
  • Protein Accession#:
  • -
  • Gene Name:
  • RET
  • Gene Alias:
  • Gene Description:
  • ret proto-oncogene
  • Gene Summary:
  • This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
  • Other Designations:
  • RET transforming sequence,cadherin family member 12,hydroxyaryl-protein kinase,oncogene RET,receptor tyrosine kinase,ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
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