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Last updated: 2017/2/19

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RENT1 Pre-design Chimera RNAi

  • Catalog # : H00005976-R01
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  • Specification
  • Product Description:
  • Homo sapiens regulator of nonsense transcripts 1 (RENT1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002911
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5976
  • Gene Name:
  • UPF1
  • Gene Alias:
  • FLJ43809,FLJ46894,HUPF1,KIAA0221,NORF1,RENT1,pNORF1
  • Gene Description:
  • UPF1 regulator of nonsense transcripts homolog (yeast)
  • Gene Summary:
  • This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq
  • Other Designations:
  • UP Frameshift 1,delta helicase,nonsense mRNA reducing factor 1,regulator of nonsense transcripts 1,up-frameshift mutation 1 homolog,yeast Upf1p homolog
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