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Last updated: 2017/6/25

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REN Pre-design Chimera RNAi

  • Catalog # : H00005972-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens renin (REN), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000537
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5972
  • Gene Name:
  • REN
  • Gene Alias:
  • FLJ10761
  • Gene Description:
  • renin
  • Gene Summary:
  • Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000034311,angiotensin-forming enzyme,angiotensinogenase,renin precursor, renal
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