ARID4A monoclonal antibody (M01), clone 2G8
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More Files
- More Functions
Immunofluorescence
Immunofluorescence of monoclonal antibody to ARID4A on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.51 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ARID4A.
Immunogen
ARID4A (NP_002883, 1033 a.a. ~ 1139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLAR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (82)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ARID4A on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ARID4A
Entrez GeneID
5926GeneBank Accession#
NM_002892Protein Accession#
NP_002883Gene Name
ARID4A
Gene Alias
RBBP1, RBP-1, RBP1
Gene Description
AT rich interactive domain 4A (RBP1-like)
Omim ID
180201Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [provided by RefSeq
Other Designations
retinoblastoma binding protein 1|retinoblastoma-binding protein 1
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