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RANGAP1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005905-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-RANGAP1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 63.5
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-RANGAP1 antibody (H00005905-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005905-T01
    RANGAP1 transfected lysate.
    Western Blot
    QC Testing of H00005905-T01
    Lane 1: RANGAP1 transfected lysate ( 63.5 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5905
  • Protein Accession#:
  • -
  • Gene Name:
  • RANGAP1
  • Gene Alias:
  • Fug1,KIAA1835,MGC20266,SD
  • Gene Description:
  • Ran GTPase activating protein 1
  • Gene Summary:
  • RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028918,segregation distorter homolog,segregation distortion
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