RANBP1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RANBP1 expression in transfected 293T cell line (H00005902-T01) by RANBP1 MaxPab polyclonal antibody.
Lane 1: RANBP1 transfected lysate(22.11 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RANBP1 protein.
Immunogen
RANBP1 (CAK54587.1, 1 a.a. ~ 201 a.a) full-length human protein.
Sequence
MAAAKDTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGAIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEKQ
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RANBP1 expression in transfected 293T cell line (H00005902-T01) by RANBP1 MaxPab polyclonal antibody.
Lane 1: RANBP1 transfected lysate(22.11 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RANBP1
Entrez GeneID
5902GeneBank Accession#
CU013156Protein Accession#
CAK54587.1Gene Name
RANBP1
Gene Alias
HTF9A, MGC88701
Gene Description
RAN binding protein 1
Omim ID
601180Gene Ontology
HyperlinkGene Summary
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq
Other Designations
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Interactome
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Disease
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