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Last updated: 2017/7/23

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RAD51C (Human) Recombinant Protein (P01)

  • Catalog # : H00005889-P01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human RAD51C full-length ORF ( AAH00667.1, 1 a.a. - 134 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQL
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 40.48
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00005889-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 5889
  • Gene Name:
  • RAD51C
  • Gene Alias:
  • MGC104277,RAD51L2
  • Gene Description:
  • RAD51 homolog C (S. cerevisiae)
  • Gene Summary:
  • This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • DNA repair protein RAD51 homolog 3,RAD51 homolog C,RAD51 homolog C, isoform 1,yeast RAD51 homolog 3
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