RAD51 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human RAD51.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00005888-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-RAD51 (100 ug)
2. Detection antibody: mouse purified polyclonal anti-RAD51 (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — RAD51
Entrez GeneID
5888Gene Name
RAD51
Gene Alias
BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
Gene Description
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BRCA1/BRCA2-containing complex, subunit 5|DNA repair protein RAD51 homolog 1|RAD51 homolog protein|RAD51, S.cerevisiae, homolog of, A|RecA, E. coli, homolog of|RecA-like protein|recombination protein A
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Interactome
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Disease
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