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RAD21 rabbit monoclonal antibody

  • Catalog # : H00005885-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RAD21 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RAD21 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RAD21 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5885
  • GeneBank Accession#:
  • RAD21
  • Gene Name:
  • RAD21
  • Gene Alias:
  • FLJ25655,FLJ40596,HR21,HRAD21,KIAA0078,MCD1,NXP1,SCC1,hHR21
  • Gene Description:
  • RAD21 homolog (S. pombe)
  • Gene Summary:
  • The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq
  • Other Designations:
  • RAD21 homolog,nuclear matrix protein 1,protein involved in DNA double-strand break repair
  • Gene Pathway
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