Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

RAD17 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005884-T02
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-RAD17 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 66.2
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-RAD17 antibody (H00005884-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005884-T02
    RAD17 transfected lysate.
    Western Blot
    QC Testing of H00005884-T02
    Lane 1: RAD17 transfected lysate ( 66.20 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5884
  • Gene Name:
  • RAD17
  • Gene Alias:
  • CCYC,FLJ41520,HRAD17,R24L,RAD17SP,RAD24
  • Gene Description:
  • RAD17 homolog (S. pombe)
  • Gene Summary:
  • The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000125189,OTTHUMP00000125190,OTTHUMP00000125192,OTTHUMP00000125193,OTTHUMP00000125194,RAD1 homolog,RAD17 homolog,RF-C activator 1 homolog,Rad17-like protein,cell cycle checkpoint protein (RAD17)
  • RSS
  • YouTube
  • Linkedin
  • Facebook