MAP4K2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
MAP4K2 transfected lysate.
Western Blot
Lane 1: MAP4K2 transfected lysate ( 90.31 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MAP4K2 full-length
Host
Human
Theoretical MW (kDa)
90.31
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MAP4K2 antibody (H00005871-B01) by Western Blots.
SDS-PAGE Gel
MAP4K2 transfected lysate.
Western Blot
Lane 1: MAP4K2 transfected lysate ( 90.31 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MAP4K2
Entrez GeneID
5871GeneBank Accession#
NM_004579Protein Accession#
NP_004570Gene Name
MAP4K2
Gene Alias
BL44, GCK, RAB8IP
Gene Description
mitogen-activated protein kinase kinase kinase kinase 2
Omim ID
603166Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq
Other Designations
B lymphocyte serine/threonine protein kinase|Rab8 interacting protein|germinal centre kinase (GC kinase)
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Interactome
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Disease
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