RAB1A monoclonal antibody (M07A), clone 3F10
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant RAB1A.
Immunogen
RAB1A (NP_004152.1, 106 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — RAB1A
Entrez GeneID
5861GeneBank Accession#
NM_004161Protein Accession#
NP_004152.1Gene Name
RAB1A
Gene Alias
DKFZp564B163, RAB1, YPT1
Gene Description
RAB1A, member RAS oncogene family
Omim ID
179508Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq
Other Designations
GTP binding protein Rab1a|RAB1, member RAS oncogene family|Rab GTPase YPT1 homolog
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Interactomes
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Publication Reference
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Rab1A Is an mTORC1 Activator and a Colorectal Oncogene.
Thomas JD, Zhang YJ, Wei YH, Cho JH, Morris LE, Wang HY, Zheng XF.
Cancer Cell 2014 Nov; 26(5):754.
Application:IF, Human, HEK293E-GM130-GFP.
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Rab1A Is an mTORC1 Activator and a Colorectal Oncogene.
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