QDPR (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human QDPR full-length ORF ( AAH00576, 1 a.a. - 244 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQADQVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTELTPAYF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
52.58
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — QDPR
Entrez GeneID
5860GeneBank Accession#
BC000576Protein Accession#
AAH00576Gene Name
QDPR
Gene Alias
DHPR, FLJ42391, PKU2, SDR33C1
Gene Description
quinoid dihydropteridine reductase
Omim ID
261630Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq
Other Designations
6,7-dihydropteridine reductase|short chain dehydrogenase/reductase family 33C, member 1
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Interactome
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Pathway
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Disease
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