PYGM monoclonal antibody (M02), clone 3D8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PYGM.
Immunogen
PYGM (NP_005600.1, 734 a.a. ~ 842 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEDYIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEAI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PYGM is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PYGM
Entrez GeneID
5837GeneBank Accession#
NM_005609Protein Accession#
NP_005600.1Gene Name
PYGM
Gene Alias
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Gene Description
phosphorylase, glycogen, muscle
Gene Ontology
HyperlinkGene Summary
This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants
Other Designations
McArdle syndrome|glycogen phosphorylase|glycogen storage disease type V|myophosphorylase|phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)
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Interactome
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Pathway
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Disease
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