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ALDH18A1 Pre-design Chimera RNAi

  • Catalog # : H00005832-R04
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens aldehyde dehydrogenase 18 family, member A1 (ALDH18A1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001017423
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5832
  • Gene Name:
  • ALDH18A1
  • Gene Alias:
  • GSAS,MGC117316,P5CS,PYCS
  • Gene Description:
  • aldehyde dehydrogenase 18 family, member A1
  • Gene Summary:
  • This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020159,OTTHUMP00000020160,delta1-pyrroline-5-carboxlate synthetase,glutamate gamma-semialdehyde synthetase,pyrroline-5-carboxlate synthetase,pyrroline-5-carboxylate synthetase,pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde sy
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