PYCR1 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human PYCR1 full-length ORF ( NP_008838.2, 1 a.a. - 319 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PYCR1
Entrez GeneID
5831GeneBank Accession#
NM_006907.2Protein Accession#
NP_008838.2Gene Name
PYCR1
Gene Alias
P5C, P5CR, PIG45, PP222, PYCR
Gene Description
pyrroline-5-carboxylate reductase 1
Omim ID
179035Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P5C reductase|proliferation-inducing protein 45
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Interactomes
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Pathways
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