PYCR1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PYCR1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PYCR1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PYCR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PYCR1
Entrez GeneID
5831GeneBank Accession#
PYCR1Gene Name
PYCR1
Gene Alias
P5C, P5CR, PIG45, PP222, PYCR
Gene Description
pyrroline-5-carboxylate reductase 1
Omim ID
179035Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P5C reductase|proliferation-inducing protein 45
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Interactome
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Pathway
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