PYCR1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
PYCR1 MaxPab polyclonal antibody. Western Blot analysis of PYCR1 expression in U-2 OS.
Western Blot (Transfected lysate)
Western Blot analysis of PYCR1 expression in transfected 293T cell line (H00005831-T01) by PYCR1 MaxPab polyclonal antibody.
Lane 1: PYCR1 transfected lysate(35.09 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PYCR1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PYCR1 protein.
Immunogen
PYCR1 (NP_008838.2, 1 a.a. ~ 319 a.a) full-length human protein.
Sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PYCR1 MaxPab polyclonal antibody. Western Blot analysis of PYCR1 expression in U-2 OS.Western Blot (Transfected lysate)
Western Blot analysis of PYCR1 expression in transfected 293T cell line (H00005831-T01) by PYCR1 MaxPab polyclonal antibody.
Lane 1: PYCR1 transfected lysate(35.09 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PYCR1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PYCR1
Entrez GeneID
5831GeneBank Accession#
NM_006907.2Protein Accession#
NP_008838.2Gene Name
PYCR1
Gene Alias
P5C, P5CR, PIG45, PP222, PYCR
Gene Description
pyrroline-5-carboxylate reductase 1
Omim ID
179035Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P5C reductase|proliferation-inducing protein 45
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Interactome
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Pathway
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Publication Reference
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Functional specialization in proline biosynthesis of melanoma.
De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW.
PLoS One 2012 Sep; 7(9):e45190.
Application：WB-Ce, Human, Human melanocytes, Lu1205 cells, Melanoma cells.
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Functional specialization in proline biosynthesis of melanoma.
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