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PEX5 Pre-design Chimera RNAi

  • Catalog # : H00005830-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens peroxisomal biogenesis factor 5 (PEX5), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000319
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5830
  • Gene Name:
  • PEX5
  • Gene Alias:
  • FLJ50634,FLJ50721,FLJ51948,PTS1-BP,PTS1R,PXR1
  • Gene Description:
  • peroxisomal biogenesis factor 5
  • Gene Summary:
  • The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • peroxin-5,peroxisomal C-terminal targeting signal import receptor,peroxisomal targeting signal 1 (SKL type) receptor,peroxisomal targeting signal import receptor,peroxisomal targeting signal receptor 1,peroxisome receptor 1
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