PEX19 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PEX19 full-length
Host
Human
Theoretical MW (kDa)
33
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PEX19 antibody (H00005824-B02P) by Western Blots.
SDS-PAGE Gel
PEX19 transfected lysate.
Western Blot
Lane 1: PEX19 transfected lysate ( 33.00 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PEX19
Entrez GeneID
5824GeneBank Accession#
BC000496.2Protein Accession#
AAH00496.1Gene Name
PEX19
Gene Alias
D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1
Gene Description
peroxisomal biogenesis factor 19
Gene Ontology
HyperlinkGene Summary
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq
Other Designations
OTTHUMP00000031848|housekeeping gene, 33kD|peroxisomal farnesylated protein
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