PVRL2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PVRL2 protein.
Immunogen
PVRL2 (NP_002847.1, 1 a.a. ~ 479 a.a) full-length human protein.
Sequence
MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDPVFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PVRL2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PVRL2 expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of PVRL2 expression in transfected 293T cell line (H00005819-T01) by PVRL2 MaxPab polyclonal antibody.
Lane 1: PVRL2 transfected lysate(51.40 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PVRL2
Entrez GeneID
5819GeneBank Accession#
NM_002856.2Protein Accession#
NP_002847.1Gene Name
PVRL2
Gene Alias
CD112, HVEB, PRR2, PVRR2
Gene Description
poliovirus receptor-related 2 (herpesvirus entry mediator B)
Omim ID
600798Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
herpesvirus entry mediator B|herpesvirus entry protein B|nectin 2|poliovirus receptor related 2|poliovirus receptor-like 2
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Interactome
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Pathway
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Disease
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