PVR 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PVR transfected lysate.
Western Blot
Lane 1: PVR transfected lysate ( 45.30 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PVR full-length
Host
Human
Theoretical MW (kDa)
45.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PVR antibody (H00005817-D01P) by Western Blots.
SDS-PAGE Gel
PVR transfected lysate.
Western Blot
Lane 1: PVR transfected lysate ( 45.30 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PVR
Entrez GeneID
5817GeneBank Accession#
NM_006505Protein Accession#
NP_006496.2Gene Name
PVR
Gene Alias
CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Gene Description
poliovirus receptor
Omim ID
173850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
nectin-like 5
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Interactome
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Pathway
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Disease
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