PURA (Human) Recombinant Protein (Q02)
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More Files
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Specification
Product Description
Human PURA partial ORF ( NP_005850.1, 92 a.a. - 141 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
30.91
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PURA
Entrez GeneID
5813GeneBank Accession#
NM_005859Protein Accession#
NP_005850.1Gene Name
PURA
Gene Alias
PUR-ALPHA, PUR1, PURALPHA
Gene Description
purine-rich element binding protein A
Omim ID
600473Gene Ontology
HyperlinkGene Summary
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq
Other Designations
purine-rich single-stranded DNA-binding protein alpha|transcriptional activator protein PUR-alpha
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Interactome
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Disease
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