PURA monoclonal antibody (M10A), clone 3B7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PURA.
Immunogen
PURA (NP_005850.1, 92 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — PURA
Entrez GeneID
5813GeneBank Accession#
NM_005859Protein Accession#
NP_005850.1Gene Name
PURA
Gene Alias
PUR-ALPHA, PUR1, PURALPHA
Gene Description
purine-rich element binding protein A
Omim ID
600473Gene Ontology
HyperlinkGene Summary
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq
Other Designations
purine-rich single-stranded DNA-binding protein alpha|transcriptional activator protein PUR-alpha
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Interactome
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Disease
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