PTS (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PTS partial ORF ( NP_000308, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PTS
Entrez GeneID
5805GeneBank Accession#
NM_000317Protein Accession#
NP_000308Gene Name
PTS
Gene Alias
FLJ97081, PTPS
Gene Description
6-pyruvoyltetrahydropterin synthase
Omim ID
261640Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq
Other Designations
6-pyruvoyl tetrahydrobiopterin synthase|6-pyruvoyl-tetrahydropterin synthase|PTP synthase
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Interactome
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Pathway
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Disease
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