PTPRN 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PTPRN transfected lysate.
Western Blot
Lane 1: PTPRN transfected lysate ( 102.80 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PTPRN full-length
Host
Human
Theoretical MW (kDa)
102.8
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PTPRN antibody (H00005798-D01P) by Western Blots.
SDS-PAGE Gel
PTPRN transfected lysate.
Western Blot
Lane 1: PTPRN transfected lysate ( 102.80 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PTPRN
Entrez GeneID
5798GeneBank Accession#
BC070053Protein Accession#
AAH70053.1Gene Name
PTPRN
Gene Alias
FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Gene Description
protein tyrosine phosphatase, receptor type, N
Omim ID
601773Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq
Other Designations
islet cell antigen 2|islet cell antigen 512|islet cell autoantigen 3|protein tyrosine phosphatase-like N
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Interactome
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Disease
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