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PTPRJ Pre-design Chimera RNAi

  • Catalog # : H00005795-R01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens protein tyrosine phosphatase, receptor type, J (PTPRJ), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002843
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5795
  • Gene Name:
  • PTPRJ
  • Gene Alias:
  • CD148,DEP1,HPTPeta,R-PTP-ETA,SCC1
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, J
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD148 antigen,human density enhanced phosphatase-1,protein tyrosine phosphatase, receptor type, J polypeptide,receptor-type tyrosine-protein phosphatase eta,susceptibility to colon cancer 1, mouse, homolog of
  • Gene Pathway
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