PTPRE polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PTPRE.
Immunogen
PTPRE (AAH50062, 511 a.a. ~ 600 a.a) partial recombinant protein with GST tag.
Sequence
WRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (91)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.01 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PTPRE polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of PTPRE expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PTPRE
Entrez GeneID
5791GeneBank Accession#
BC050062Protein Accession#
AAH50062Gene Name
PTPRE
Gene Alias
DKFZp313F1310, FLJ57799, FLJ58245, HPTPE, PTPE, R-PTP-EPSILON
Gene Description
protein tyrosine phosphatase, receptor type, E
Omim ID
600926Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq
Other Designations
OTTHUMP00000020735|OTTHUMP00000020736|protein tyrosine phosphatase epsilon|protein tyrosine phosphatase, receptor type, epsilon polypeptide
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Interactome
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