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PTPRB Pre-design Chimera RNAi

  • Catalog # : H00005787-R03
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens protein tyrosine phosphatase, receptor type, B (PTPRB), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002837
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5787
  • Gene Name:
  • PTPRB
  • Gene Alias:
  • DKFZp686E2262,DKFZp686H15164,FLJ44133,HPTP-BETA,HPTPB,MGC142023,MGC59935,PTPB,R-PTP-BETA,VEPTP
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, B
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • protein tyrosine phosphatase, receptor type, beta polypeptide
  • Gene Pathway
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