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PTPN13 Pre-design Chimera RNAi

  • Catalog # : H00005783-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006264
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5783
  • Gene Name:
  • PTPN13
  • Gene Alias:
  • DKFZp686J1497,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq
  • Other Designations:
  • APO-1/CD95 (Fas)-associated phosphatase,Fas-associated phosphatase-1,protein tyrosine phosphatase 1E,protein tyrosine phosphatase, non-receptor type 13,protein tyrosine phosphatase, nonreceptor type 13,protein-tyrosine phosphatase 1, Fas-associated,protei
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