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PTPN12 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005782-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PTPN12 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 85.91
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PTPN12 antibody (H00005782-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005782-T01
    PTPN12 transfected lysate.
    Western Blot
    QC Testing of H00005782-T01
    Lane 1: PTPN12 transfected lysate ( 85.91 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5782
  • Protein Accession#:
  • -
  • Gene Name:
  • PTPN12
  • Gene Alias:
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 12
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025119,protein-tyrosine phosphatase G1,tyrosine-protein phosphatase non-receptor type 12
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