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PTPN11 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005781-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PTPN11 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 52.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PTPN11 antibody (H00005781-B02) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005781-T02
    PTPN11 transfected lysate
    Western Blot
    QC Testing of H00005781-T02
    Lane 1: PTPN11 transfected lysate ( 52.8 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5781
  • Gene Name:
  • PTPN11
  • Gene Alias:
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 11
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq
  • Other Designations:
  • protein tyrosine phosphatase-2,protein-tyrosine phosphatase 2C
  • Interactome
  • Interactome
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