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PTPN2 (Human) IP-WB Antibody Pair

  • Catalog # : H00005771-PW2
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00005771-PW2
    Immunoprecipitation of PTPN2 transfected lysate using rabbit polyclonal anti-PTPN2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PTPN2.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-PTPN2 (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-PTPN2 (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5771
  • Gene Name:
  • PTPN2
  • Gene Alias:
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. [provided by RefSeq
  • Other Designations:
  • T-cell protein tyrosine phosphatase
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